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[接触碘后发生甲状腺危象。1例致死病例]

[Thyrotoxic crisis after exposure to iodine. A case with fatal outcome].

作者信息

Blattmann H, Reinhardt M, Schümichen C, Moser E

机构信息

Abteilung Nuklearmedizin, Radiologische Universitätsklinik Freiburg.

出版信息

Radiologe. 1994 Aug;34(8):487-90.

PMID:7972728
Abstract

A 78-year-old woman is presented with a multinodular toxic goiter and euthyroidism under continuous low-dose treatment with antithyroid drugs. A period of hyperthyroidism had been documented 3 years previously. In the preoperative management, prior to resection of a benign ovarian tumour, an intravenous urogram was performed. Perchlorate was given for thyroid protection. One day after surgery the clinical signs of thyroid storm were observed. Immediately, high-dose antithyroid drug therapy was started. Nevertheless, the patient died of acute cardiovascular failure 3 days later. This case report focuses on the risk of thyroid storm following iodine excess in the presence of relevant functional thyroid autonomy without adequate thyroid protection.

摘要

一名78岁女性患有多结节毒性甲状腺肿,在持续低剂量抗甲状腺药物治疗下甲状腺功能正常。3年前曾记录有一段甲状腺功能亢进期。在术前管理中,在切除良性卵巢肿瘤之前,进行了静脉肾盂造影。给予高氯酸盐以保护甲状腺。术后一天观察到甲状腺危象的临床症状。立即开始高剂量抗甲状腺药物治疗。然而,患者在3天后死于急性心血管衰竭。本病例报告重点关注在存在相关功能性甲状腺自主性且没有充分甲状腺保护的情况下,碘过量后发生甲状腺危象的风险。

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