Kadoya M, Matsui O, Kitagawa K, Kawamori Y, Yoshikawa J, Gabata T, Miyayama S, Takashima T
Department of Radiology, Kanazawa University School of Medicine, Japan.
Radiology. 1994 Dec;193(3):671-6. doi: 10.1148/radiology.193.3.7972806.
To evaluate the causes of intrahepatic segmental areas of signal hypointensity [corrected] on T1- and T2-weighted spin-echo (SE) and gradient-echo (GRE) magnetic resonance (MR) images.
Six patients in whom wedge-shaped hypointense areas were seen on hepatic MR images underwent examination with ultrasound (US), computed tomography (CT), angiography, and CT during arterial portography (CTAP). Histologic examination was performed in three patients.
The affected liver parenchymas were best depicted as segmental or lobar hypointense areas on GRE images. Angiography and CTAP revealed that portal blood supply to the hypointense areas was absent or decreased due to portal vein tumor thrombus and arterioportal shunt (n = 1), compression of a portal branch by tumor (n = 2), portal vein thrombosis (n = 1), or arterioportal shunt (n = 2). Iron deposition in the hepatocytes was evident in all three patients with histologic correlation.
Segmental signal hypocoagulability was generally due to hepatocyte iron deposition and was accompanied and possibly caused by a disturbance in portal flow.
评估在T1加权和T2加权自旋回波（SE）及梯度回波（GRE）磁共振（MR）图像上肝内节段性信号低强度区域的原因。
6例肝脏MR图像上可见楔形低强度区域的患者接受了超声（US）、计算机断层扫描（CT）、血管造影以及动脉门静脉造影CT（CTAP）检查。3例患者进行了组织学检查。
在GRE图像上，受影响的肝实质表现为最佳的节段性或叶性低强度区域。血管造影和CTAP显示，由于门静脉肿瘤血栓形成和动静脉分流（n = 1）、肿瘤压迫门静脉分支（n = 2）、门静脉血栓形成（n = 1）或动静脉分流（n = 2），低强度区域的门静脉血供缺失或减少。在所有3例有组织学相关性的患者中，肝细胞内铁沉积明显。
节段性信号低凝性一般归因于肝细胞铁沉积，并伴有门静脉血流紊乱且可能由其所致。
