Nakakoshi T, Matsuzawa H, Houkin K, Miyasaka K, Arimoto T
Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan.
Radiat Med. 1994 May-Jun;12(3):139-42.
Proton magnetic resonance spectroscopy (1H-MRS) is thought to be more sensitive to radiation damage of the brain than magnetic resonance imaging (MRI). We presented performed 1H-MRS using the stimulated echo acquisition method (STEAM) for non-tumor sites in 2 patients who received radiation therapy for their brain tumors. In the first case up to 45 days after radiation, we could observe a normal spectra presented three major peaks of N-acetyl aspartate (NAA), creatine and phosphocreatine (Cr), and choline (Cho). In the second case who had radiation necrosis 1 year after radiation, the spectra showed a decrease in the all peaks beneath the noise level.
质子磁共振波谱（1H-MRS）被认为对脑辐射损伤比磁共振成像（MRI）更敏感。我们对2例接受脑肿瘤放射治疗的患者的非肿瘤部位采用刺激回波采集法（STEAM）进行了1H-MRS检查。在第一例中，放疗后长达45天，我们可以观察到正常光谱呈现出N-乙酰天门冬氨酸（NAA）、肌酸和磷酸肌酸（Cr）以及胆碱（Cho）的三个主要峰。在第二例放疗后1年出现放射性坏死的病例中，光谱显示所有峰均降至噪声水平以下。
