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[几种先天性畸形的复发风险:无脑儿、脊柱裂、腭裂和唇裂]

[Risk of recurrence of several congenital malformations: anencephaly, spina bifida, cleft palate and cleft lip].

作者信息

Bonaiti-Pellie C, Feingold J, Briard M L, Frezal J

出版信息

Arch Fr Pediatr. 1976 Dec;33(10):973-86.

PMID:797342
Abstract

Recurrence risks were estimated for some congenital malformation from a multifactorial model according to the method given by Smith (1971). Risks were estimated for cleft lip with or without cleft palate, cleft palate alone, anencephaly and spina bifida from data on frequency and heritability collected in France. Results are given in tables representing risks for some 180 specific family histories.

摘要

根据史密斯(1971年)给出的方法,从多因素模型中估计了一些先天性畸形的复发风险。利用在法国收集的关于发病率和遗传度的数据,对唇裂伴或不伴腭裂、单纯腭裂、无脑儿和脊柱裂的风险进行了估计。结果列于表格中,这些表格展示了约180种特定家族病史的风险。

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