[Ultrastructural changes in mucosa of the distal portion of the large intestine of patients with dysentery].

The ultrastructure of the mucosa of the large intestine was studied in 10 patients with acute dysentery. The group of patients included 7 women and 3 men aged 17--50 years. Diagnosis was confirmed in all cases bacteriologically (by isolation of Sonne shigella in 4 patients and Flexner shigella in 6 patients). The electron-microscopy study of bioptats of the mucosa showed that in the inflammatory process all its cells--prismatic, gobletcells, and enterochromaffin -- took part, although not in the same degree. Early appearance of a great number of prismatic cells with a high functional activity indicated to compensatory abilities of the mucosa already during the first days of the disease.