Chinowsky M S
Department of Internal-Medicine, Kaiser Permanente Medical Center, Harbor City, Calif. 90710.
South Med J. 1994 Nov;87(11):1168-71. doi: 10.1097/00007611-199411000-00025.
Thrombotic thrombocytopenic purpura (TTP) complicated a vaso-occlusive crisis in a patient with sickle cell-hemoglobin C (HbSC) disease. Markedly abnormal HbSC red blood cell morphology confused the initial diagnostic evaluation of the peripheral smear. Sustained, severe thrombocytopenia and the patient's failure to respond clinically to RBC exchange transfusion helped to indicate the proper diagnosis that led to effective therapy.
血栓性血小板减少性紫癜（TTP）并发于一名镰状细胞-血红蛋白C（HbSC）病患者的血管闭塞性危机。显著异常的HbSC红细胞形态使外周血涂片的初步诊断评估变得复杂。持续性严重血小板减少以及患者对红细胞置换输血无临床反应，有助于明确正确诊断，从而得以进行有效治疗。
