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[心脏手术和血管手术中抗生素预防与伤口感染的发生情况]

[Antibiotic prevention and occurrence of wound infections in heart surgery and vascular surgery].

作者信息

Andersen K S, Kvitting P M, Harthug S

机构信息

Thoraxkirurgisk seksjon, Haukeland Sykehus, Bergen.

出版信息

Tidsskr Nor Laegeforen. 1994 Oct 30;114(26):3071-4.

PMID:7974426
Abstract

Post-operative wound infections are serious complications in cardiovascular surgery. In order to examine the routines for prophylactic antibiotics and frequency of wound infections, questionnaires were sent to heart and vascular surgery units in Norway. In heart surgery, the sternal wound infection rate registered during stay in hospital varied between 0-1.2%. Seven clinics used cephalothin prophylaxis and one cloxacillin and penicillin. One clinic added vancomycin in the case of valvular surgery. The duration of prophylaxis varied from six hours to four days. In vascular surgery, superficial wound infection rates of 1.5-4.0%, and deep infection rates of 0.8-2.0%, were reported. Seven clinics used cephalothin and three cefuroxime as prophylaxis. The duration of prophylaxis varied from one single dose to several days. In conclusion, the reported infection rates indicate that the antibiotic prophylaxis regimens used help to provide satisfactory protection against wound infections.

摘要

术后伤口感染是心血管手术中的严重并发症。为了研究预防性使用抗生素的常规做法以及伤口感染的发生率,向挪威的心脏和血管外科科室发放了调查问卷。在心脏手术中,住院期间记录的胸骨伤口感染率在0%-1.2%之间。七个诊所使用头孢噻吩进行预防,一个诊所使用氯唑西林和青霉素。一个诊所对于瓣膜手术加用了万古霉素。预防用药的持续时间从6小时到4天不等。在血管手术中,报告的浅表伤口感染率为1.5%-4.0%,深部感染率为0.8%-2.0%。七个诊所使用头孢噻吩,三个诊所使用头孢呋辛进行预防。预防用药的持续时间从单次剂量到数天不等。总之,报告的感染率表明所使用的抗生素预防方案有助于提供令人满意的伤口感染防护。

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