转移性肾癌的管理

Management of disseminated kidney cancer.

作者信息

Taneja S S, Pierce W, Figlin R, Belldegrun A

机构信息

Division of Urology, University of California, Los Angeles School of Medicine.

出版信息

Urol Clin North Am. 1994 Nov;21(4):625-37.

PMID:7974894

Abstract

The approach to disseminate renal cell carcinoma (RCC) has evolved significantly in recent years, largely owing to the progress of biologic therapy development. With increasing knowledge of biologic therapy come several dilemmas, including the choice of cytokine therapy, the appropriate mode of delivery, the selection of candidates for given therapeutic options, and the role of cytoreductive nephrectomy in immunotherapy protocols. This article reviews the historical development of immunotherapy and the lessons learned from previous experience and offers a logical approach to the patient with disseminated RCC.

摘要

近年来，转移性肾细胞癌（RCC）的治疗方法有了显著进展，这在很大程度上归功于生物治疗的发展。随着对生物治疗的了解不断增加，出现了几个难题，包括细胞因子治疗的选择、合适的给药方式、特定治疗方案候选者的选择以及减瘤性肾切除术在免疫治疗方案中的作用。本文回顾了免疫治疗的历史发展以及从以往经验中吸取的教训，并为转移性RCC患者提供了一种合理的治疗方法。