Shlygin G K, Gapparov M M, Vasilevskaia L S, Sokolov A I, Popova Iu P, Nemaia M A, Tishin D E
Vopr Pitan. 1993 Jan-Feb(1):18-22.
Dog experiments have established that an initial period of food-induced thermogenesis (FIT) has a reflex nature. This is proved by FIT appearance in sham feeding and disappearance after atropine administration. Various food substances proved capable of evoking this reflex. It was also registered in humans. Oxygen consumption rose within 3-10 minutes after a test meal reaching a 25% maximal increment. However, no or minimal manifestations of the reflex occurred in obese patients. They had to undergo a 30-day weight-reducing treatment to reacquire the lost reflex. Physiological value of FIT as a mechanism stimulating tissue metabolism and preparing food substances assimilation are discussed.
犬类实验已证实,食物诱导产热(FIT)的初始阶段具有反射性质。假饲时出现FIT以及给予阿托品后FIT消失证明了这一点。各种食物物质都被证明能够引发这种反射。在人类身上也有记录。试餐后3 - 10分钟内耗氧量增加,最大增幅达到25%。然而,肥胖患者没有或仅有最小程度的反射表现。他们必须接受30天的减重治疗才能重新获得丧失的反射。文中讨论了FIT作为刺激组织代谢和促进食物物质同化的一种机制的生理价值。