大剂量静脉注射丙种球蛋白治疗获得性血管性血友病的疗效
Effectiveness of high-dose intravenous gamma globulin therapy in acquired von Willebrand's disease.
作者信息
van Genderen P J, Michiels J J, Bakker J J, van 't Veer M B
机构信息
Department of Haematology, University Hospital Dijkzigt, Rotterdam, The Netherlands.
出版信息
Vox Sang. 1994;67(1):14-7. doi: 10.1111/j.1423-0410.1994.tb05030.x.
Abstract
An 82-year-old patient with acquired von Willebrand's disease in association with a non-Hodgkin's lymphoma and a benign IgG-lambda monoclonal paraproteinemia is described with severe recurring nasopharyngeal bleedings, who responded poorly to desmopressin (DDAVP) and factor VIII/von Willebrand factor concentrates but was successfully treated with high-dose e intravenous gamma-globulin therapy.
摘要
本文描述了一名82岁的患者，患有获得性血管性血友病，合并非霍奇金淋巴瘤和良性IgG-λ单克隆副蛋白血症，伴有严重复发性鼻出血，对去氨加压素（DDAVP）和凝血因子VIII/血管性血友病因子浓缩物反应不佳，但经大剂量静脉注射γ-球蛋白治疗成功。
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