Stawiski M A, Voorhees J J
Cutis. 1976 Sep;18(3):415-21.
Cutaneous signs of diabetes mellitus are extremely valuable to both the clinician and the researcher. Lesions such as necrobiosis lipoidica diabeticorum, diabetic dermopathy, carotenemia idiopathic bullous eruptions of granuloma anulare alert the physician to consider the diagnosis of diabetes mellitus. Xanthomas reflect the status of glucose and lipid metabolism. Diabetic dermopathy might be a useful monitor of angiopathic changes in the heart, kidney and brain. Finally, the accessibility of the skin makes it an ideal organ for studying the pathogenesis of diabetes and the effect of medications on the vascular and neurological complications of diabetes.
糖尿病的皮肤症状对临床医生和研究人员都极具价值。诸如糖尿病性类脂质渐进性坏死、糖尿病性皮肤病、胡萝卜素血症、特发性大疱性皮疹、环状肉芽肿等病变,会提醒医生考虑糖尿病的诊断。黄瘤反映了葡萄糖和脂质代谢的状况。糖尿病性皮肤病可能是心脏、肾脏和脑部血管病变的有用监测指标。最后,皮肤易于获取,这使其成为研究糖尿病发病机制以及药物对糖尿病血管和神经并发症影响的理想器官。