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冠状动脉内线圈(Gianturco-Roubin)支架治疗球囊血管成形术后急性夹层的初步临床经验。

Initial clinical experience of intracoronary coil (Gianturco-Roubin) stents for management of acute dissection after balloon angioplasty.

作者信息

Shim W H, Ha J W, Cho S Y, Park S H, Kim H S, Jang Y S, Chung N, Kim S S

机构信息

Department of Internal Medicine, Yonsei Cardiovascular Center, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Yonsei Med J. 1994 Sep;35(3):320-8. doi: 10.3349/ymj.1994.35.3.320.

DOI:10.3349/ymj.1994.35.3.320
PMID:7975741
Abstract

Dissections after percutaneous transluminal coronary angioplasty (PTCA) are risk factors for acute or subacute vessel closures. Intracoronary stenting was developed to avoid these complications by pressing the intimal and medial flaps against the vessel wall, thus reducing the risk of acute closure from thrombus formation. Thirty three coil (Gianturco-Roubin) stents were implanted into the coronary arteries of 32 patients with dissections after PTCA during the period of March 1993 to December 1993. The indications for stent implantation were acute closure in 6 (18.8%), threatened closure in 6 (18.8%) and suboptimal result in 20 (62.4%) patients. Stent insertion were successful in 30 (94%) patients. The diameter stenosis in an immediate angiographic findings after stenting was decreased from 87% to 18% by caliper estimation. Emergency coronary artery bypass graft surgery was required in 1 (3%) patient. A non-Q wave myocardial infarction occurred in 1 (3%) patient. Complications included hematoma of the arterial access site requiring blood transfusion in 4 (12.5%) patients and hemopericardium in 1 (3%) patient. Our initial clinical experience of flexible coil coronary stent imply that stenting is efficacious treatment for acute dissections that are causing acute or threatened closure following angioplasty. The long term follow-up result in all groups of patient who received coronary stents is needed for better evaluation of new devices and prognosis.

摘要

经皮腔内冠状动脉成形术(PTCA)后的血管夹层是急性或亚急性血管闭塞的危险因素。冠状动脉内支架置入术的发展是为了通过将内膜和中膜瓣片压向血管壁来避免这些并发症,从而降低血栓形成导致急性闭塞的风险。在1993年3月至1993年12月期间,将33个线圈(Gianturco-Roubin)支架植入32例PTCA术后出现血管夹层的患者的冠状动脉中。支架植入的适应证为急性闭塞6例(18.8%)、濒临闭塞6例(18.8%)和效果欠佳20例(62.4%)。30例(94%)患者支架置入成功。支架置入后即刻血管造影显示,通过卡尺测量,直径狭窄率从87%降至18%。1例(3%)患者需要急诊冠状动脉旁路移植术。1例(3%)患者发生非Q波心肌梗死。并发症包括4例(12.5%)动脉穿刺部位血肿需输血和1例(3%)患者心包积血。我们对柔性线圈冠状动脉支架的初步临床经验表明,支架置入术是治疗血管成形术后导致急性或濒临闭塞的急性夹层的有效方法。为了更好地评估新器械和预后,需要对所有接受冠状动脉支架置入的患者组进行长期随访。

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