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一项比较达他可的松、咪康唑和氢化可的松治疗炎性皮肤感染的双盲研究。

A double-blind study comparing Daktacort, miconazole and hydrocortisone in inflammatory skin infections.

作者信息

Mertens R L, Morias J, Verhamme G

出版信息

Dermatologica. 1976;153(4):228-35. doi: 10.1159/000251061.

Abstract

In a 4-week double-blind trial, Daktacort cream was compared with each of its constituents (i.e. miconazole 2% and hydrocortisone 1%) in a total of 63 patients (aged 12-60 years) with inflamed skin infections of bacterial or mycotic origin. Daktacort treatment induced a significant improvement of all symptoms within 1 week and was superior to both miconazole and hydrocortisone in suppressing the inflammation. This tendency persisted throughout the trial but at the end miconazole treatment proved also superior to hydrocortisone.

摘要

在一项为期4周的双盲试验中,对63名年龄在12至60岁之间、患有细菌性或真菌性皮肤感染炎症的患者,将达可宁乳膏与其各成分(即2%咪康唑和1%氢化可的松)进行了比较。达可宁治疗在1周内使所有症状显著改善,在抑制炎症方面优于咪康唑和氢化可的松。这一趋势在整个试验过程中持续存在,但在试验结束时,咪康唑治疗也证明优于氢化可的松。

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