κ-硒化卡拉胶对大鼠红细胞膜流动性及血影重封能力的影响。
Effects of kappa-selenocarrageenan on membrane fluidity and ghost reseal ability of rat erythrocyte.
作者信息
Li D, Han Q, Yang X Y, Rong D M, Lin Z J
机构信息
Department of Pharmacology, School of Pharmacy, Shanghai Medical University, China.
出版信息
Zhongguo Yao Li Xue Bao. 1994 May;15(3):211-4.
Effects of kappa-selenocarrageenan (kappa-SeC) on membrane fluidity and ghost reseal ability of rat erythrocyte were studied by measuring the fluorescence polarization and the NADH-cytochrome C oxido-reductase, respectively. After rats were given ig kappa-SeC 140 mg.kg-1.d-1 x 30 d, the fluorescence polarization was decreased in comparison with saline control group (P < 0.05). It suggested that kappa-SeC increased the membrane fluidity. The reseal ability of erythrocyte membrane (ghost) was also elevated after ig kappa-SeC 140 and 70 mg.kg-1.d-1 x 30 d (P < 0.05).
分别通过测量荧光偏振和NADH-细胞色素C氧化还原酶，研究了κ-硒化卡拉胶（κ-SeC）对大鼠红细胞膜流动性和血影重封能力的影响。大鼠经口给予κ-SeC 140 mg·kg-1·d-1×30 d后，与生理盐水对照组相比，荧光偏振降低（P<0.05）。这表明κ-SeC增加了膜流动性。大鼠经口给予κ-SeC 140和70 mg·kg-1·d-1×30 d后，红细胞膜（血影）的重封能力也提高了（P<0.05）。
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