Wong M T, Chang P C, Yu Y L, Chan Y W, Chan V
Department of Psychiatry, University of Hong Kong.
Acta Psychiatr Scand. 1994 Jul;90(1):16-8. doi: 10.1111/j.1600-0447.1994.tb01549.x.
Twenty-eight asymptomatic relatives from 7 Chinese families with Huntington's disease (HD) received psychosocial assessment. One third of these subjects (n = 9) had symptoms of anxiety and depression that warranted a Present State Examination (PSE) diagnosis. One quarter of these subjects (n = 8) would contemplate suicide if their predictive testing indicated a high risk of having the disease. This suicidal risk was associated with a PSE diagnosis of depression and a stress-coping repertoire with a high proportion of coping strategies of the avoidance type at the time of interview. Early and close liaison with these subjects for the detection of mental symptoms and provision of counselling on a balanced and positive coping style is essential.
对来自7个患有亨廷顿舞蹈症（HD）的中国家庭的28名无症状亲属进行了社会心理评估。这些受试者中有三分之一（n = 9）有焦虑和抑郁症状，需要进行现状检查（PSE）诊断。这些受试者中有四分之一（n = 8）表示，如果预测性检测表明他们患该病的风险很高，他们会考虑自杀。这种自杀风险与PSE诊断的抑郁症以及在访谈时具有高比例回避型应对策略的压力应对方式有关。早期与这些受试者密切联系，以发现精神症状并就平衡和积极的应对方式提供咨询至关重要。
