Ito U, Tomita H, Tone O, Masaoka H, Tominaga B
Department of Neurosurgery, Musashino Red Cross Hospital, Tokyo.
Acta Neurochir Suppl (Wien). 1994;60:361-4. doi: 10.1007/978-3-7091-9334-1_97.
The propagation of extravasated contrast medium around 6 supratentorial meningiomas with peritumoral white matter of low density (PWL) of Lanksch II-III was investigated by repeated CT scanning at 4 h intervals, following a 1 h drip infusion of 200 ml of Iopamidol. The volume of the expanding peritumoral contrast enhancement was calculated according to a method previously described. By calculating the increase in volume from the first to the second scan, and from the second to third, we derived the rate of edema formation as well as the resolution rate of edema in the PWL. The surface area of the entire tumor (TS) and area of tumor surface facing the PWL (LS) were calculated by summating the surface areas of all CT slices, each area of which was derived from the measured length of the entire circumference of the tumor and circumference of the tumor facing the PWL, respectively, multiplied by the slice thickness of 0.5 cm. The volume of PWL, edema formation rate of entire tumor, and tumor volume x LS/TS were well correlated with each other. We concluded that the severity of peritumoral edema in meningiomas depends on the size of the tumor and the extent of tumor surface contact with the PWL.
在静脉滴注200毫升碘帕醇1小时后，每隔4小时进行重复CT扫描，研究了6例幕上脑膜瘤周围伴有Lanksch II - III级瘤周低密度白质（PWL）的外渗造影剂的扩散情况。根据先前描述的方法计算瘤周强化范围的扩大体积。通过计算第一次扫描到第二次扫描以及第二次扫描到第三次扫描的体积增加量，我们得出了水肿形成率以及PWL中水肿的消退率。通过将所有CT层面的表面积相加来计算整个肿瘤的表面积（TS）和肿瘤表面面向PWL的面积（LS），每个层面的面积分别由测量的肿瘤整个周长和面向PWL的肿瘤周长乘以0.5厘米的层面厚度得出。PWL的体积、整个肿瘤的水肿形成率以及肿瘤体积×LS/TS之间相互具有良好的相关性。我们得出结论，脑膜瘤瘤周水肿的严重程度取决于肿瘤的大小以及肿瘤表面与PWL接触的范围。
