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不孕女性的常规甲状腺功能检查:有必要吗?

Routine thyroid function tests in infertile women: are they necessary?

作者信息

Shalev E, Eliyahu S, Ziv M, Ben-Ami M

机构信息

Department of Obstetrics and Gynecology, Central Emek Hospital, Afula, Israel.

出版信息

Am J Obstet Gynecol. 1994 Nov;171(5):1191-2. doi: 10.1016/0002-9378(94)90130-9.

DOI:10.1016/0002-9378(94)90130-9
PMID:7977517
Abstract

To investigate the yield of routine thyroid function testing in infertile women, the records of 444 infertile women were categorized to standard infertility groups. Thyroid function was evaluated by measuring plasma free thyroxine and thyroid-stimulating hormone. All free thyroxine values were in the normal range (0.8 to 1.8 ng/ml), and only three thyroid-stimulating hormone values were higher than the normal range (0.15 to 4.5 mIU/L). The three women had ovulatory dysfunction. Thyroid function testing is more prudent in screening the subset of infertile women with ovulatory dysfunction and not as a routine measure in the infertile population.

摘要

为研究常规甲状腺功能检测在不孕女性中的检出率,将444例不孕女性的记录分类到标准不孕组。通过检测血浆游离甲状腺素和促甲状腺激素来评估甲状腺功能。所有游离甲状腺素值均在正常范围内(0.8至1.8 ng/ml),只有3例促甲状腺激素值高于正常范围(0.15至4.5 mIU/L)。这3名女性存在排卵功能障碍。甲状腺功能检测在筛查有排卵功能障碍的不孕女性亚组时更应谨慎,而不应作为不孕人群的常规检测手段。

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引用本文的文献

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Effect of the Cut-Off Level for Thyroid-Stimulating Hormone on the Prevalence of Subclinical Hypothyroidism among Infertile Mexican Women.促甲状腺激素临界值对墨西哥不孕女性亚临床甲状腺功能减退症患病率的影响。
Diagnostics (Basel). 2021 Mar 1;11(3):417. doi: 10.3390/diagnostics11030417.
2
In vitro fertilization pregnancy rates in levothyroxine-treated women with hypothyroidism compared to women without thyroid dysfunction disorders.甲状腺功能减退症患者经左甲状腺素治疗后的体外受精妊娠率与无甲状腺功能障碍疾病患者的比较。
Thyroid. 2012 Jun;22(6):631-6. doi: 10.1089/thy.2011.0343. Epub 2012 Apr 27.
3
Evaluation of hormonal testing in the screening for in vitro fertilization (IVF) of women with tubal factor infertility.
输卵管因素不孕症女性体外受精(IVF)筛查中激素检测的评估。
J Assist Reprod Genet. 1995 Feb;12(2):93-6. doi: 10.1007/BF02211376.