Sun H, Kuban B D, Schmalbrock P, Friedman M H
Biomedical Engineering Center, Ohio State University, Columbus 43210.
Ann Biomed Eng. 1994 May-Jun;22(3):229-39. doi: 10.1007/BF02368230.
This paper presents a method for measuring arterial geometry in vivo using MRI. The approach was validated using MR images of three perfused compliant casts of human aortic bifurcations whose geometry was known. Preliminary human studies demonstrated the reproducibility of the technique. The approach was applied to 20 normal individuals to study the effects of age, race, and gender on the geometry of the aortic bifurcation. The results show that older people tend to have a smaller bifurcation angle, lower planarity, and larger angular asymmetry than younger people. Asians have larger bifurcation angles than whites. The bifurcation of males is more asymmetric than that of females. These results may have implications regarding the heritability of arterial geometry, the similarities of cardiovascular risk within families, and differences in risk among groups.
本文介绍了一种利用磁共振成像（MRI）在体内测量动脉几何形状的方法。该方法通过对三个已知几何形状的人体主动脉分叉灌注顺应性模型的磁共振图像进行验证。初步人体研究证明了该技术的可重复性。该方法应用于20名正常个体，以研究年龄、种族和性别对主动脉分叉几何形状的影响。结果表明，老年人的分叉角度往往比年轻人小，平面度较低，角度不对称性较大。亚洲人的分叉角度比白人更大。男性的分叉比女性更不对称。这些结果可能对动脉几何形状的遗传性、家庭中心血管风险的相似性以及不同群体之间的风险差异具有启示意义。
