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内镜下经胸交感神经切除术:治疗多汗症效果良好,但适应证能否扩大?

Endoscopic transthoracic sympathectomy: successful in hyperhidrosis but can the indications be extended?

作者信息

Nicholson M L, Dennis M J, Hopkinson B R

机构信息

Department of Surgery, University Hospital Nottingham.

出版信息

Ann R Coll Surg Engl. 1994 Sep;76(5):311-4.

Abstract

Endoscopic transthoracic sympathectomy (ETS) has recently become established as a successful treatment for severe palmar and axillary hyperhidrosis. In this unit the indications for ETS have been broadened to include patients with Raynaud's syndrome and critical upper limb ischaemia and this paper is primarily concerned with analysing outcome in relation to the indication for operation. In all, 68 operations have been attempted in 40 patients and complete follow-up details are available on 62 treated limbs. One operation was a technical failure because of an obliterated pleural cavity. In the hyperhidrosis group (n = 28), all the affected areas showed symptomatic improvement at a median follow-up of 17 months. In the Raynaud's group (n = 30), 28 limbs (93%) were improved to some degree at the time of discharge, but at a median follow-up of 18 months only 15 limbs (50%) remained symtomatically improved to some degree. The four upper limbs treated for critical ischaemia were improved by ETS and no amputations were necessary. Significant postoperative chest pain was noted by nine patients (23%). There were three postoperative pneumothoraces, two intercostobrachial neuralgias and one transient Horner's syndrome. The cosmetic result was reported as excellent or good by 97% of patients. As with other forms of surgical thoracic sympathectomy, excellent early results are not maintained in the longer term when ETS is used to treat Raynaud's syndrome. Nevertheless, the greater simplicity and lower morbidity of the endoscopic method suggest that it can be offered to Raynaud's sufferers with greater impunity than open sympathectomies.

摘要

内镜下胸交感神经切除术(ETS)最近已成为治疗重度手掌和腋窝多汗症的一种成功方法。在本治疗组中,ETS的适应证已扩大到包括雷诺综合征和严重上肢缺血患者,本文主要关注分析与手术适应证相关的治疗结果。总共对40例患者进行了68次手术,62条接受治疗的肢体有完整的随访细节。有1例手术因胸膜腔闭塞而技术失败。在多汗症组(n = 28),所有受累区域在中位随访17个月时症状均有改善。在雷诺综合征组(n = 30),28条肢体(93%)在出院时有所改善,但在中位随访18个月时,只有15条肢体(50%)仍有一定程度的症状改善。接受治疗的4条严重缺血上肢经ETS治疗后病情改善,无需截肢。9例患者(23%)术后出现明显胸痛。术后发生3例气胸、2例肋间臂神经痛和1例短暂性霍纳综合征。97%的患者报告美容效果为优或良。与其他形式的胸交感神经切除术一样,当ETS用于治疗雷诺综合征时,长期来看并不能维持良好的早期效果。然而,内镜方法更简便且发病率更低,这表明与开放性交感神经切除术相比,它可以更安全地应用于雷诺综合征患者。

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本文引用的文献

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J R Coll Surg Edinb. 1985 Aug;30(4):221-3.

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