Patt R B
University of Texas MD Anderson Cancer Center, Section of Pain and Symptom Management, Houston 77030.
Ann Acad Med Singap. 1994 Jul;23(4):598-609.
Cancer pain is prevalent and undertreated despite the availability of therapeutic options that, taken together are highly effective, economical and safe. Improved understanding of the pharmacology of chronically-administered opioids has resulted in reduced concerns about addiction and an increased emphasis on their use. The anaesthetist may play a pivotal role in cancer pain management by the provision of nerve blocks and other interventions, but, to be a truly effective consultant, must also be expert in all aspects of pharmacotherapy. A rationale for the development of pharmacologic expertise together with a review of assessment and pharmacologic management of cancer pain are provided.
尽管有多种治疗选择，它们综合起来高效、经济且安全，但癌症疼痛仍然普遍存在且治疗不足。对长期使用阿片类药物药理学的进一步了解，减少了对成瘾问题的担忧，并更加重视其使用。麻醉医生可通过提供神经阻滞和其他干预措施在癌症疼痛管理中发挥关键作用，但要成为真正有效的顾问，还必须在药物治疗的各个方面都成为专家。本文提供了培养药理学专业知识的理论依据，以及对癌症疼痛评估和药物管理的综述。
