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[对临床局限于前列腺的腺癌(T1至T3N0M0)进行根治性外照射放疗:至少4年随访的中期结果]

[External radiotherapy with curative intent for adenocarcinoma clinically localized to the prostate (T1 to T3N0M0): intermediate results with a minimum follow-up of 4 years].

作者信息

Rohner S, Bieri S, Graber P

机构信息

Clinique d'Urologie (Département de Chirurgie), Hôpital Cantonal Universitaire de Genève, Suisse.

出版信息

Ann Urol (Paris). 1994;28(4):221-8.

PMID:7979212
Abstract

External beam radiation therapy is a well-established alternative to radical surgery for the treatment of clinically localized prostate cancer. However, many recent studies suggest that this treatment fails to eradicate prostatic tumors. Outcomes in 100 patients treated in a single institution are reported herein. Follow-up was at least four years in every case. Although survival rates were comparable to or greater than those reported in earlier studies, rates of local and distant recurrences were high, indicating poor treatment efficacy. These data suggest that radiation therapy is not an acceptable alternative to radical surgery for the curative treatment of localized prostatic carcinoma.

摘要

体外放射治疗是治疗临床局限性前列腺癌的一种成熟的根治性手术替代方案。然而,最近的许多研究表明,这种治疗方法无法根除前列腺肿瘤。本文报告了在单一机构接受治疗的100例患者的治疗结果。每例患者的随访时间至少为四年。尽管生存率与早期研究报告的相当或更高,但局部和远处复发率很高,表明治疗效果不佳。这些数据表明,对于局限性前列腺癌的根治性治疗,放射治疗不是根治性手术可接受的替代方案。

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