Reid M, Hammersley R
Behavioural Sciences Group, University of Glasgow, UK.
Appetite. 1994 Jun;22(3):221-31. doi: 10.1006/appe.1994.1021.
Energy intake was estimated from the food diaries of 52 overnight-fasted adult volunteers after ingestion of 110 ml of a solution of either 40 g of sucrose or 4.34 g of saccharin administered in blind conditions. Men consumed more calories and carbohydrates than women. Women's eating was unaffected by the preload. The sucrose preload led to 60% of male subjects choosing to consume a calorific beverage soon afterwards; they then delayed eating compared to men who received a saccharin preload. Men who had received sucrose, but consumed no beverage, ate as early as the saccharin preload group. It is concluded that under fasted, blind administration followed by everyday eating, sucrose does not increase hunger, but eating behaviour after a preload varies with eating habits.
能量摄入是根据52名成年志愿者在空腹过夜后摄入110毫升溶液（溶液中含有40克蔗糖或4.34克糖精，且给药条件为盲法）的食物日记估算得出的。男性摄入的卡路里和碳水化合物比女性多。女性的饮食不受预负荷的影响。蔗糖预负荷导致60%的男性受试者随后选择饮用高热量饮料；与接受糖精预负荷的男性相比，他们随后延迟了进食时间。接受蔗糖但未饮用饮料的男性，进食时间与糖精预负荷组一样早。得出的结论是，在空腹、盲法给药后进行日常饮食的情况下，蔗糖不会增加饥饿感，但预负荷后的饮食行为会因饮食习惯而异。
