Uderzo C, van Lint M T, Rovelli A, Weber G, Castellani M R, Bacigalupo A, Masera N, Cohen A
Department of Paediatric Haematology and Oncology, S Gerardo Hospital, University of Milan, Monza, Italy.
Arch Dis Child. 1994 Sep;71(3):256-8. doi: 10.1136/adc.71.3.256.
Two children developed papillary thyroid carcinoma after allogeneic bone marrow transplantation (BMT) probably due to radiotherapy during remission and pretransplantation conditioning. Establishing a relationship between the cellular thyroid stimulating hormone (TSH) effect and development of carcinoma in cases with high serum TSH concentrations is difficult. After BMT, patients should be regularly followed up with thyroid ultrasound and, when nodularity is found, fine needle aspiration and/or open biopsy are recommended.
两名儿童在接受异基因骨髓移植(BMT)后发生了乳头状甲状腺癌,这可能是由于缓解期放疗和移植前预处理所致。在血清促甲状腺激素(TSH)浓度较高的病例中,很难确定细胞性促甲状腺激素(TSH)效应与癌症发生之间的关系。骨髓移植后,应对患者定期进行甲状腺超声检查,发现结节时,建议进行细针穿刺抽吸活检和/或开放性活检。