Blanche C, Valenza M, Czer L S, Barath P, Admon D, Harasty D, Utley C, Freimark D, Aleksic I, Matloff J
Department of Cardiothoracic Surgery, Cedars-Sinai Medical Center, Los Angeles, California 90048.
Ann Thorac Surg. 1994 Nov;58(5):1505-9. doi: 10.1016/0003-4975(94)91944-5.
We present our experience with an alternative technique for orthotopic heart transplantation. It consists of total excision of the recipient's atria, with the donor's heart implantation performed using bicaval end-to-end anastomoses as well as pulmonary venous anastomoses. Forty consecutive patients receiving transplants in this fashion were compared with 64 patients who underwent orthotopic transplantation with the standard technique. The incidence of postoperative tricuspid regurgitation was reduced in patients receiving transplants with the new surgical approach (p = 0.003). In addition, the need for pacemaker implantation for severe bradyarrhythmia in the early (0 to 6 weeks) posttransplantation period (p = 0.003) was eliminated. Although not statistically significant, there was a trend in the reduction of postoperative mitral regurgitation in patients who received transplants by the modified technique. Based on this experience, we believe this modified technique for orthotopic heart transplantation has an anatomic and physiologic advantage that may improve long-term hemodynamic results.
我们介绍了一种原位心脏移植替代技术的经验。该技术包括完全切除受者心房,采用双腔静脉端端吻合及肺静脉吻合进行供体心脏植入。将连续40例采用这种方式接受移植的患者与64例采用标准技术进行原位移植的患者进行了比较。采用新手术方法进行移植的患者术后三尖瓣反流的发生率降低(p = 0.003)。此外,消除了移植后早期(0至6周)因严重缓慢性心律失常而植入起搏器的需求(p = 0.003)。虽然无统计学意义,但采用改良技术进行移植的患者术后二尖瓣反流有减少的趋势。基于这一经验,我们认为这种改良的原位心脏移植技术具有解剖学和生理学优势,可能会改善长期血流动力学结果。