Smirnov A V, Sokolova I N, Volkova L D
Arkh Patol. 1993 Mar-Apr;55(2):31-8.
22 cases of clear cell sarcoma of the kidney (CCSK) were studied, 15 of them ultrastructurally and 7--immunohistochemically. CCSK is a rare malignant tumour of children, predominantly males, with an involvement of one kidney and frequent multiple metastases to the bones. Typical, epithelioid-trabecular, hyalinizing, cystic and myxoid variants are distinguished at the light microscopic level. As vimentin was found in tumour cells in all cases, antibodies against vimentin and cytokeratin can be recommended for differential diagnosis between CCSK and Wilms tumour and rhabdoid tumour. Peculiar vascular pattern can be revealed by means of antibodies against factor VIII. Immunohistochemical properties (presence of vimentin) and electron microscopy allow suggesting histogenic relation of CCSK with pericytes.
对22例肾透明细胞肉瘤（CCSK）进行了研究，其中15例进行了超微结构研究，7例进行了免疫组织化学研究。CCSK是一种罕见的儿童恶性肿瘤，以男性为主，累及一侧肾脏，且常发生骨转移。在光学显微镜水平可区分出典型型、上皮样小梁型、玻璃样变性型、囊性型和黏液样变型。由于在所有病例的肿瘤细胞中均发现波形蛋白，因此推荐使用抗波形蛋白和细胞角蛋白的抗体进行CCSK与肾母细胞瘤及横纹肌样瘤的鉴别诊断。通过抗因子VIII抗体可显示出特殊的血管模式。免疫组织化学特性（波形蛋白的存在）和电子显微镜检查提示CCSK与周细胞存在组织发生学关系。
