Ziangirova G G, Antonova O V, Fedorov A A
Arkh Patol. 1993 Mar-Apr;55(2):44-7.
26 intraocular melanomas were studied histologically, ultrastructurally and morphometrically. For the first time the impregnation method was used for visualization of the nucleolar organizer (NO) in the cells of eye tumors using silver salts on the deparaffined sections. The efficiency and reliability of this method in the determination of the degree of malignancy of intraocular melanomas are demonstrated. A correlation existed between long-term postoperative results and the nucleolar organizer index (NO number/number of nuclei). The method can be practiced in any pathohistologic laboratory.
对26例眼内黑色素瘤进行了组织学、超微结构和形态计量学研究。首次在脱蜡切片上使用银盐浸渍法,通过银盐使眼肿瘤细胞中的核仁组织者(NO)可视化。证明了该方法在确定眼内黑色素瘤恶性程度方面的有效性和可靠性。术后长期结果与核仁组织者指数(NO数量/细胞核数量)之间存在相关性。该方法可在任何病理组织学实验室实施。