Mambrito B, Arabia M, Chieco S, Ferrazzi P, Ferri E, Fierli M, Glauber M, Meli M, Zagara M
Tecnobiomedica S.p.A., Rome, Italy.
Artif Organs. 1994 Jul;18(7):533-6. doi: 10.1111/j.1525-1594.1994.tb03373.x.
In Italy, artificial heart development was promoted by virtue of a special program on technological and industrial development in areas related to cardiology and cardiosurgery. A first prototype series of electromechanical total artificial hearts (TAHs) and ventricular assist devices (VADs), with ball-screw-based actuation technology, has been developed, and preliminary bench tests and short-term animal implant experiments were performed. The project started with analysis and development of existing TAH and VAD models, and it included a fill-sensor-free control scheme and anatomical fitting studies using a three-dimensional computer model of the chest cavity. Second-generation prototypes are currently being developed, and they are scheduled for medium-term bench and in vivo testing by early 1994.
在意大利，人造心脏的研发借助了一项关于心脏病学和心脏外科相关领域技术与产业发展的特别计划得以推进。已经开发出了首批采用基于滚珠丝杠驱动技术的机电式全人工心脏（TAH）和心室辅助装置（VAD）的原型系列，并进行了初步的台架试验和短期动物植入实验。该项目始于对现有TAH和VAD模型的分析与开发，包括一种无填充传感器的控制方案以及利用胸腔三维计算机模型进行的解剖学适配研究。目前正在开发第二代原型，计划于1994年初进行中期台架试验和体内测试。
