Mischke R
Klinik für kleine Haustiere, Tierärztlichen Hochschule Hannover.
Berl Munch Tierarztl Wochenschr. 1994 Sep;107(9):289-94.
The activity of the coagulation factors II, V, VII and X was measured in plasmas of 167 healthy dogs of different age, sex and breeds using a test optimized for dogs. During the first months of life particularly the factor X-activity, but also the activity of factor-II-, and by way of suggestion the factor V-activity was lower in comparison to adult dogs. A dependence on the sex was only seen for the factor II- (p = 0.0497) and V-activity (p = 0.0467), which was slightly higher in not castrated female than in male dogs. Significant differences between different breeds existed for factor VII. With regard to a collective of different breeds the reference values (2.5- and 97.5%-quantile) were calculated for adult dogs (n = 111). Especially the range of the factor VII- (62-180%), and also of factor V-activity (68-137%) was wider than that of the factor II- (84-126%) and factor X-activity (77-121%).
采用针对犬类优化的检测方法，对167只不同年龄、性别和品种的健康犬的血浆中凝血因子II、V、VII和X的活性进行了测定。在生命的最初几个月里，尤其是X因子活性，还有II因子活性，推测V因子活性与成年犬相比更低。仅发现II因子（p = 0.0497）和V因子活性（p = 0.0467）存在性别依赖性，未绝育雌性犬的这两种因子活性略高于雄性犬。不同品种之间VII因子存在显著差异。针对不同品种的犬类群体，计算了成年犬（n = 111）的参考值（第2.5和97.5百分位数）。特别是VII因子活性范围（62 - 180%），以及V因子活性范围（68 - 137%）比II因子（84 - 126%）和X因子活性范围（77 - 121%）更宽。
