[Activity of coagulation factors II, V, VII and X in healthy dogs--dependence on age, sex and breed].

The activity of the coagulation factors II, V, VII and X was measured in plasmas of 167 healthy dogs of different age, sex and breeds using a test optimized for dogs. During the first months of life particularly the factor X-activity, but also the activity of factor-II-, and by way of suggestion the factor V-activity was lower in comparison to adult dogs. A dependence on the sex was only seen for the factor II- (p = 0.0497) and V-activity (p = 0.0467), which was slightly higher in not castrated female than in male dogs. Significant differences between different breeds existed for factor VII. With regard to a collective of different breeds the reference values (2.5- and 97.5%-quantile) were calculated for adult dogs (n = 111). Especially the range of the factor VII- (62-180%), and also of factor V-activity (68-137%) was wider than that of the factor II- (84-126%) and factor X-activity (77-121%).