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酵母线粒体基因组的组织与进化

Organization and evolution of the mitochondrial genome of yeast.

作者信息

Bernardi G

出版信息

J Mol Evol. 1976 Dec 31;9(1):25-35. doi: 10.1007/BF01796120.

DOI:10.1007/BF01796120
PMID:798040
Abstract

The mitochondrial genome of yeast (S. cerevisiae or S. carlsbergensis) appears to be formed by 60-70 genetic units, each one of which is formed by (1) a GC-rich sequence, possibly having a regulatory role; (2) a gene, and (3) an AT-rich spacer, which probably is not transcribed. Recombination in this genome appears to underlie a number of important phenomena. The organization of the mitochondrial genome of yeast and these recombinational events are discussed in relationship with the organization and evolution of the nuclear genome of eukaryotes.

摘要

酵母（酿酒酵母或卡尔斯伯酵母）的线粒体基因组似乎由60 - 70个遗传单位组成，其中每个单位由以下部分构成：（1）一个富含GC的序列，可能具有调控作用；（2）一个基因；以及（3）一个富含AT的间隔区，该区段可能不被转录。该基因组中的重组似乎是许多重要现象的基础。本文讨论了酵母线粒体基因组的组织方式以及这些重组事件与真核生物核基因组的组织和进化之间的关系。

相似文献

1
Organization and evolution of the mitochondrial genome of yeast.酵母线粒体基因组的组织与进化
J Mol Evol. 1976 Dec 31;9(1):25-35. doi: 10.1007/BF01796120.
2
Mitochondrial recombination in crosses of iso- and anisomitochondrial Saccharomyces cerevisiae.同线粒体和异线粒体酿酒酵母杂交中的线粒体重组
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The mitochondrial genome of wild-type yeast cells. VII. Recombination in crosses.
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Assembly of the mitochondrial membrane system: mutations in the pho2 locus of the mitochondrial genome of Saccharomyces cerevisiae.线粒体膜系统的组装：酿酒酵母线粒体基因组pho2位点的突变
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The mitochondrial genome of wild-type yeast cells. V. Genome evolution.
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Protein overexport in a Saccharomyces cerevisiae mutant depends on mitochondrial genome integrity and function.酿酒酵母突变体中的蛋白质过度输出取决于线粒体基因组的完整性和功能。
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Mitochondrial genetics in Bakers' yeast: a molecular mechanism for recombinational polarity and suppressiveness.面包酵母中的线粒体遗传学：重组极性和抑制性的分子机制。
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On the formation of rho- petites in yeast. I. Multifactorial mitochondrial crosses (rho+ X rho+) involving a mutation conferring temperature-sensitivity of rho factor stability.关于酵母中ρ-小菌落的形成。I. 涉及赋予ρ因子稳定性温度敏感性突变的多因子线粒体杂交（ρ⁺×ρ⁺）
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Genetic analysis of unequal transmission of the mitochondrial markers in Saccharomyces cerevisiae.酿酒酵母中线粒体标记不均等传递的遗传分析。
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Mitochondrial genetics. XI. Mutations at the mitochondrial locus omega affecting the recombination of mitochondrial genes in Saccharomyces cerevisiae.线粒体遗传学。十一。酿酒酵母中线粒体ω位点的突变影响线粒体基因的重组
Mol Gen Genet. 1976 Jan 16;143(2):131-65. doi: 10.1007/BF00266918.

引用本文的文献

1
A Dynamic Mobile DNA Family in the Yeast Mitochondrial Genome.酵母线粒体基因组中的一个动态移动DNA家族
G3 (Bethesda). 2015 Apr 20;5(6):1273-82. doi: 10.1534/g3.115.017822.
2
Propagation of restriction fragments from the mitochondrial DNA of Saccharomyces cerevisiae in E. coli by means of plasmid vectors.通过质粒载体在大肠杆菌中繁殖来自酿酒酵母线粒体DNA的限制性片段。
Nucleic Acids Res. 1979;6(6):2133-50. doi: 10.1093/nar/6.6.2133.

本文引用的文献

1
Dimeric structure and allosteric properties of spleen acid deoxyribonuclease.脾酸脱氧核糖核酸酶的二聚体结构和别构性质
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Separation and characterization of a satellite DNA from a yeast cytoplasmic "petite" mutant.从酵母细胞质“小菌落”突变体中分离和鉴定卫星DNA
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Characterization of some unusual DNAs from the mitochondria from certain "petite" strains of Saccharomyces cerevisiae.来自酿酒酵母某些“小菌落”菌株线粒体的一些异常DNA的特征分析。
Arch Biochem Biophys. 1968 Dec;128(3):685-703. doi: 10.1016/0003-9861(68)90078-7.
4
Mitochondrial DNA's from respiratory-sufficient and cytoplasmic respiratory-deficient mutant yeast.来自呼吸充足和细胞质呼吸缺陷型突变酵母的线粒体DNA。
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5
Optical rotatory dispersion and circular dichroism properties of yeast mitochondrial DNA's.
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6
The mitochondrial genome of wild-type yeast cells. IV. Genes and spacers.野生型酵母细胞的线粒体基因组。IV. 基因与间隔区。
J Mol Biol. 1974 Jul 15;86(4):825-41. doi: 10.1016/0022-2836(74)90356-8.
7
The mitochondrial genome of wild-type yeast cells. 3. The pyrimidine tracts of mitochondrial DNA.野生型酵母细胞的线粒体基因组。3. 线粒体DNA的嘧啶序列。
J Mol Biol. 1972 Mar 28;65(2):207-12. doi: 10.1016/0022-2836(72)90277-x.
8
The mitochondrial genome of wild-type yeast cells. II. Investigations on the compositional heterogeneity of mitochondrial DNA.野生型酵母细胞的线粒体基因组。II. 线粒体DNA组成异质性的研究。
J Mol Biol. 1972 Mar 28;65(2):191-205. doi: 10.1016/0022-2836(72)90276-8.
9
The mitochondrial genome of wild-type yeast cells. I. Preparation and heterogeneity of mitochondrial DNA.野生型酵母细胞的线粒体基因组。I. 线粒体DNA的制备与异质性
J Mol Biol. 1972 Mar 28;65(2):173-89. doi: 10.1016/0022-2836(72)90275-6.
10
The number of 4-S RNA genes on yeast mitochondrial DNA.酵母线粒体DNA上4-S RNA基因的数量。
Biochem Biophys Res Commun. 1972 Apr 14;47(1):126-33. doi: 10.1016/s0006-291x(72)80019-6.