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无神经精神性狼疮病史的系统性红斑狼疮患者的磁共振成像

Magnetic resonance imaging in systemic lupus erythematosus patients without a history of neuropsychiatric lupus erythematosus.

作者信息

Jarek M J, West S G, Baker M R, Rak K M

机构信息

Department of Medicine, Fitzsimons Army Medical Center, Aurora, CO 80045-5001.

出版信息

Arthritis Rheum. 1994 Nov;37(11):1609-13. doi: 10.1002/art.1780371108.

DOI:10.1002/art.1780371108
PMID:7980671
Abstract

OBJECTIVE

To determine the prevalence of magnetic resonance imaging (MRI) lesions in systemic lupus erythematosus (SLE) patients without a history of neuropsychiatric symptoms and to correlate any MRI abnormalities with the patient's other disease manifestations or treatment.

METHODS

Prospective study of 32 consecutive patients with SLE without a history of neuropsychiatric symptoms, from inpatient and outpatient rheumatology services, who underwent MRI scan during a 3-year period.

RESULTS

Five patients had MRI abnormalities consisting of white matter lesions or periventricular hyperintensities; this is similar to the prevalence of these abnormalities in the general population.

CONCLUSION

The prevalence of silent brain MRI abnormalities is not increased in SLE patients who do not have a history of neuropsychiatric manifestations.

摘要

目的

确定无神经精神症状病史的系统性红斑狼疮(SLE)患者中磁共振成像(MRI)病变的患病率,并将任何MRI异常与患者的其他疾病表现或治疗相关联。

方法

对连续32例无神经精神症状病史的SLE患者进行前瞻性研究,这些患者来自住院和门诊风湿病科,在3年期间接受了MRI扫描。

结果

5例患者存在MRI异常,包括白质病变或脑室周围高信号;这与一般人群中这些异常的患病率相似。

结论

无神经精神表现病史的SLE患者中无症状脑MRI异常的患病率并未增加。

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Cortical thickness and subcortical gray matter reductions in neuropsychiatric systemic lupus erythematosus.
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