Hill J, Bird H A, Harmer R, Wright V, Lawton C
Clinical Pharmacology Unit, University Department of Medicine, Royal Bath Hospital, Harrogate.
Br J Rheumatol. 1994 Mar;33(3):283-8. doi: 10.1093/rheumatology/33.3.283.
Seventy patients with RA were randomly allocated to either a Rheumatology Nurse Practitioner (RNP) or Consultant Rheumatologist (CR) clinic. They were seen on six occasions in 1 year. Effectiveness and safety were assessed by biochemical, clinical, psychological and functional variables; patient knowledge and satisfaction were measured by questionnaire. At week 0 the groups were well matched clinically and demographically. By week 48 significant improvements had occurred in plasma viscosity and articular index within both groups. In patients managed by the RNP, pain, morning stiffness, psychological status, patient knowledge and satisfaction had all improved significantly (P = 0.001; P = 0.028; P = 0.0005; P < 0.0001; P < 0.0001 respectively), improvements not mirrored by the CR cohort. Between group comparisons also showed significant differences by the end of the study. Compared to the CR patients, the RNP suffered from lower levels of pain (P < 0.05), had acquired greater levels of knowledge (P < 0.0001) and were significantly more satisfied with their care (P < 0.0001).
70名类风湿性关节炎患者被随机分配到风湿科护士执业医师(RNP)诊所或风湿科顾问医师(CR)诊所。他们在1年内接受了6次诊治。通过生化、临床、心理和功能变量评估有效性和安全性;通过问卷调查衡量患者的知识水平和满意度。在第0周时,两组在临床和人口统计学方面匹配良好。到第48周时,两组的血浆粘度和关节指数均有显著改善。在由RNP管理的患者中,疼痛、晨僵、心理状态、患者知识水平和满意度均有显著改善(分别为P = 0.001;P = 0.028;P = 0.0005;P < 0.0001;P < 0.0001),而CR组未出现类似改善。组间比较在研究结束时也显示出显著差异。与CR组患者相比,RNP组患者的疼痛程度较低(P < 0.05),知识水平更高(P < 0.0001),并且对治疗的满意度显著更高(P < 0.0001)。