Caro J F, Besarab A, Burke J F, Glennon J A
Lancet. 1978 Aug 26;2(8087):451-4. doi: 10.1016/s0140-6736(78)91447-2.
The effect of propranolol upon parathyroid hormone (P.T.H) concentrations was investigated in patients undergoing chronic haemodialysis. 9 patients receiving propranolol for the treatment of hypertension or angina pectoris were compared with 25 similar patients not taking the drug. P.T.H. and alkaline phosphatase concentrations were lower in patients receiving propranolol and there was less radiological evidence of renal osteodystrophy in these patients. Prospective studies are needed to determine whether propranolol may be helpful as an adjunct to other therapy in reversing or preventing renal osteodystrophy.
在接受慢性血液透析的患者中，研究了普萘洛尔对甲状旁腺激素（P.T.H）浓度的影响。将9例因治疗高血压或心绞痛而服用普萘洛尔的患者与25例未服用该药的类似患者进行了比较。服用普萘洛尔的患者的P.T.H和碱性磷酸酶浓度较低，且这些患者中肾性骨营养不良的放射学证据较少。需要进行前瞻性研究以确定普萘洛尔作为其他疗法的辅助药物在逆转或预防肾性骨营养不良方面是否有帮助。
