在比较性临床试验中用于检验等效性或超等效性的曼特尔-亨塞尔型检验。
Mantel-Haenszel-type tests for testing equivalence or more than equivalence in comparative clinical trials.
作者信息
Yanagawa T, Tango T, Hiejima Y
机构信息
Department of Mathematics, Kyushu University, Fukuoka, Japan.
出版信息
Biometrics. 1994 Sep;50(3):859-64.
PMID:7981407
Abstract
This paper proposes Mantel-Haenszel-type statistics for testing whether a new treatment is at least as effective as the standard treatment in comparative binomial trials. The null hypotheses considered are of a specified nonzero difference and of a ratio not equal to unity. It is shown that we may also use these tests for testing the equivalence of two treatments.
摘要
本文提出了曼特尔 - 亨泽尔（Mantel-Haenszel）型统计量，用于在比较二项试验中检验新治疗方法是否至少与标准治疗方法一样有效。所考虑的原假设是特定的非零差异以及比率不等于1的情况。结果表明，我们也可以使用这些检验来检验两种治疗方法的等效性。
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