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玻璃体的流变学:第3部分。电解质、胶原蛋白和透明质酸的浓度。

Rheology of the vitreous body: part 3. Concentration of electrolytes, collagen and hyaluronic acid.

作者信息

Lee B, Litt M, Buchsbaum G

机构信息

Colgate-Palmolive Co., Piscataway, New Jersey.

出版信息

Biorheology. 1994 Jul-Aug;31(4):339-51. doi: 10.3233/bir-1994-31404.

DOI:10.3233/bir-1994-31404
PMID:7981434
Abstract

The vitreous body from bovine, porcine, and human eyes was analyzed for concentration of selected components. Each vitreous sample was sectioned into anterior, central, and posterior segments. The segments were analyzed for concentration of Ca+2, Cl-, Na+, and K+, as well as of Collagen and Hyaluronic acid. The four electrolytes showed significant differences between species, but no significant regional variations. The two macromolecules showed significant differences with respect to both species and region within the vitreous. Comparison of these results with previously determined rheological values for the three species revealed a number of unexpected results, such as higher polymer concentrations on average being associated with lower values of viscosity parameters. The results are analyzed in terms of possible compositional differences among species and effects of electrolytes on the viscoelastic behavior of the vitreous' macromolecules.

摘要

对来自牛眼、猪眼和人眼的玻璃体进行了选定成分浓度分析。每个玻璃体样本被切成前段、中段和后段。对这些片段分析了Ca+2、Cl-、Na+和K+以及胶原蛋白和透明质酸的浓度。这四种电解质在不同物种之间存在显著差异,但无明显的区域差异。这两种大分子在玻璃体的物种和区域方面均存在显著差异。将这些结果与先前测定的这三个物种的流变学值进行比较,发现了许多意外结果,例如平均而言较高的聚合物浓度与较低的粘度参数值相关。根据物种间可能存在的成分差异以及电解质对玻璃体大分子粘弹性行为的影响对结果进行了分析。

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