晚期乳腺癌患者的肿瘤标志物作为预后指标：一项初步研究。
Tumor markers in patients with advanced breast cancer as prognosticators: a preliminary study.
作者信息
Bhatavdekar J M, Patel D D, Karelia N H, Vora H H, Ghosh N, Shah N G, Balar D B, Trivedi S N
机构信息
Division of Research, Gujarat Cancer Society, Asarwa, Ahmedabad, India.
出版信息
Breast Cancer Res Treat. 1994;30(3):293-7. doi: 10.1007/BF00665970.
A retrospective study was performed on 69 breast cancer patients (stage II, N = 18; advanced disease, N = 51) in order to assess the prognostic value of circulating prolactin (PRL), CEA, CA 15-3, insulin-like growth factor-1 (IGF-1), and epidermal growth factor (EGF) by RIA/IRMA. These markers were compared with short-term prognosis (two years). Significant difference was observed only for PRL ( < 20.0 ng/ml vs. > 20.0 ng/ml), which provide an independent predictor of short-term prognosis in advanced breast cancer.
对69例乳腺癌患者（II期，n = 18；晚期疾病，n = 51）进行了一项回顾性研究，以通过放射免疫分析/免疫放射分析评估循环催乳素（PRL）、癌胚抗原（CEA）、CA 15 - 3、胰岛素样生长因子-1（IGF - 1）和表皮生长因子（EGF）的预后价值。将这些标志物与短期预后（两年）进行比较。仅观察到PRL有显著差异（< 20.0 ng/ml与> 20.0 ng/ml），这为晚期乳腺癌的短期预后提供了一个独立的预测指标。
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