Speiser P W, New M I
Division of Pediatric Endocrinology and Metabolism, North Shore University Hospital, Manhasset, New York.
Clin Perinatol. 1994 Sep;21(3):631-45.
Congenital adrenal hyperplasia is one of a few inherited disorders that can be managed by administering medication to the fetus via oral maternal administration. Dexamethasone given in the first trimester ameliorates genital ambiguity in the affected female fetus. Mother and fetus should be monitored during and after pregnancy for treatment-related complications. Therapy can be coordinated with prenatal diagnostic testing.
