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妊娠期大面积肺栓塞采用链激酶及经皮导管碎栓治疗。

Massive pulmonary embolism in pregnancy treated with streptokinase and percutaneous catheter fragmentation.

作者信息

Mazeika P K, Oakley C M

机构信息

Department of Medicine, Hammersmith Hospital, London, U.K.

出版信息

Eur Heart J. 1994 Sep;15(9):1281-3. doi: 10.1093/oxfordjournals.eurheartj.a060666.

DOI:10.1093/oxfordjournals.eurheartj.a060666
PMID:7982432
Abstract

Despite heightened awareness, pulmonary embolism remains a major cause of maternal mortality in the antenatal period and one which has not decreased in incidence over the four triennia since 1976. We report a patient who suffered massive pulmonary embolism with circulatory collapse in the second trimester and who was treated with intravenous streptokinase followed by percutaneous mechanical dispersion of thrombus using a catheter and guide wire. She made an excellent recovery despite complicating antepartum haemorrhage. In life-threatening circumstances pharmacological thrombolysis is mandatory particularly for hospitals without a cardiac catheterization laboratory on site.

摘要

尽管人们的认识有所提高,但肺栓塞仍是产前孕产妇死亡的主要原因之一,自1976年以来的三个三年期内其发病率并未下降。我们报告了一名患者,她在孕中期发生了伴有循环衰竭的大面积肺栓塞,接受了静脉注射链激酶治疗,随后使用导管和导丝进行经皮血栓机械分散治疗。尽管出现了产前出血的并发症,但她恢复得很好。在危及生命的情况下,药物溶栓是必要的,特别是对于没有现场心脏导管实验室的医院。

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[Massive pulmonary embolism during pregnancy treated with streptokinase and complicated by massive haemorrhage--a case report].[孕期巨大肺栓塞采用链激酶治疗并并发大出血——病例报告]
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引用本文的文献

1
The use of thrombolytic therapy in pregnancy.妊娠期间溶栓治疗的应用。
Obstet Med. 2013 Sep;6(3):105-111. doi: 10.1177/1753495X13488771. Epub 2013 Jul 25.