Thomázy V, Nagy A, Gál I, Nemes Z
Department of Pathology, University Medical School of Debrecen, Hungary.
Histopathology. 1994 Aug;25(2):165-9. doi: 10.1111/j.1365-2559.1994.tb01573.x.
Plexiform fibrohistiocytic tumour is a recently described type of fibrohistiocytic tumour, the differentiation pattern of which is poorly understood. A case representing the predominantly fibrohistiocytic type of the tumour is reported. Immunohistochemical analysis supports the histiocytic origin of this entity. The expression of EBM/11 and tissue transglutaminase both in fibroblast-like and histiocyte-like cells indicate that a single cell line produces the dual morphological features. It is proposed that a non-phagocytic epithelioid pattern of histiocytic differentiation characterizes this tumour.
丛状纤维组织细胞瘤是一种最近才被描述的纤维组织细胞瘤类型，其分化模式尚不清楚。本文报道了一例以纤维组织细胞为主型的该肿瘤病例。免疫组织化学分析支持该肿瘤的组织细胞起源。EBM/11和组织转谷氨酰胺酶在成纤维细胞样和组织细胞样细胞中的表达表明，单一细胞系产生了双重形态特征。有人提出，组织细胞分化的非吞噬性上皮样模式是该肿瘤的特征。
