Lewis J L, Poff B C, Smith J J, Lindquist C, Engebretsen L, Lew W D
Department of Orthopaedic Surgery, University of Minnesota, Minneapolis 55455.
J Orthop Res. 1994 Nov;12(6):780-8. doi: 10.1002/jor.1100120605.
In order to determine the appropriate load history for optimal remodeling of an anterior cruciate ligament graft, methods for establishing and measuring the graft force due to an external load could be set to a preselected value in in vivo are required. Our objectives with this study were to (a) develop a method in which the graft force due to an external load could be set to a preselected value in a living animal, (b) show that this force could be maintained after fixation, and (c) determine what happens to the forces after the animal has functioned for as long as 2 weeks postoperatively, when differing levels of load sharing between the segments had been set at surgery. The anterior cruciate ligament was reconstructed in 12 goats with use of a bone-patellar tendon-bone graft and a synthetic augmentation device. The forces in the graft segments were established, at the time of surgical fixation, with use of a force-setting technique. In five animals, the tendon segment was set to carry 90% of the total graft force; in the remaining seven animals, the augmentation segment was set to share 90% of the total graft force. Graft forces were measured, with the use of buckle transducers mounted extra-articularly over the anterior tibia, under a 67 N anterior tibial load at 60 degrees of knee flexion before and after fixation and at 2 weeks postoperatively.(ABSTRACT TRUNCATED AT 250 WORDS)
为了确定前交叉韧带移植物最佳重塑的合适负荷历史，需要在体内将由于外部负荷产生的移植物力的建立和测量方法设置为预选值。本研究的目的是：（a）开发一种方法，在活体动物中可将由于外部负荷产生的移植物力设置为预选值；（b）证明固定后该力能够维持；（c）确定在动物术后长达2周发挥功能时，当手术时设定了不同程度的节段间负荷分担时，力会发生什么变化。使用骨-髌腱-骨移植物和一种合成增强装置对12只山羊进行前交叉韧带重建。在手术固定时，采用力设定技术确定移植物节段中的力。在5只动物中，将肌腱节段设定为承担总移植物力的90%；在其余7只动物中，将增强节段设定为分担总移植物力的90%。在固定前后以及术后2周，在膝关节屈曲60度、67 N的胫骨前负荷下，使用安装在胫骨前方关节外的扣式传感器测量移植物力。（摘要截短于250字）
