Bataille P, Ben Hamida F, Achard J M, Dahmani F, Hakami F, Fournier A
Service de néphrologie, CHG de Boulogne-sur-Mer.
Nephrologie. 1994;15(4):289-94.
Extracorporeal shock wave lithotripsy (ESWL) has produced dramatic advances in the surgical management of urinary calculi. However this new procedure could induce deleterious effects as loss of renal function and hypertension. Animal studies show that ESWL induces focal areas of necrosis and subsequent fibrosis in renal tissue. In humans, imaging technics demonstrate renal alterations in 80% of the patients. Acute renal hemodynamic and functional changes is frequent but transient in most of the cases. Some studies have shown a tendancy to an increase in blood pressure related to a decrease in renal plasma flow in one study. However most of these results are based on retrospective surveys of blood pressure and renal function. Therefore prospective clinical trials are needed to investigate the important questions of ESWL-induced hypertension and decrease renal function.
体外冲击波碎石术（ESWL）在尿石症的外科治疗方面取得了巨大进展。然而，这种新方法可能会引发有害影响，如肾功能丧失和高血压。动物研究表明，ESWL会在肾组织中诱导局部坏死区域以及随后的纤维化。在人类中，成像技术显示80%的患者存在肾脏改变。急性肾血流动力学和功能变化很常见，但在大多数情况下是短暂的。一项研究表明，血压有升高趋势，与肾血浆流量减少有关。然而，这些结果大多基于对血压和肾功能的回顾性调查。因此，需要进行前瞻性临床试验来研究ESWL诱发高血压和肾功能下降的重要问题。
