Rotte K H, Stier M
Z Erkr Atmungsorgane. 1976 Aug;146(2):201-9.
Favourable results of the computer-aided diagnosis of peripheral bronchial carcinoma lead to a simplified scheme for calculation fo diagnosis, basing upon X-ray symptoms. This scheme was tested in the Zentralinstitut für Krebsforschung (ZIK) in 102 pateints and in the Forschungsinstitut für Lungenkrankheiten und Tuberkulose (FLT) in 101 patients. These patients had coin lesions of the lung with unknown diagnoses. The histological diagnoses later proved were compared with the calculated diagnoses. In ZIK there were correct diagnosis in 92.16% (in 96.53% of the carcinomas, in 44.4% of the tuberculomas and in all benign tumors), while in FLT 85.53% of the coin lesions were correctly classified (89.13% of carcinomas, 79.31% of the tuberculomas and all benign tumors). The comparison with the clinical-histological diagnoses showed a clear improvement of the accuracy by the calculated diagnoses. The method can be recommended for the basic diagnosis especially of peripheral bronchial carcinoma. It implies a reduction of the diagnostic delay, but it can not substitute the histologic investigation of the lesions.
外周支气管癌计算机辅助诊断的良好结果促成了一种基于X线症状的简化诊断计算方案。该方案在中央癌症研究所（ZIK）对102例患者以及在肺疾病与结核病研究所（FLT）对101例患者进行了测试。这些患者肺部有不明诊断的钱币状病变。将后来证实的组织学诊断与计算得出的诊断进行了比较。在ZIK，正确诊断率为92.16%（癌为96.53%，结核瘤为44.4%，所有良性肿瘤均正确），而在FLT，85.53%的钱币状病变被正确分类（癌为89.13%，结核瘤为79.31%，所有良性肿瘤均正确）。与临床组织学诊断的比较表明，计算得出的诊断显著提高了准确性。该方法尤其适用于外周支气管癌的初步诊断。它意味着减少诊断延迟，但不能替代对病变的组织学检查。
