Kadanoff D, Wassilev W, Matev I
Z Mikrosk Anat Forsch. 1976;90(1):16-28.
Various areas in 7 local flaps and in 6 free skin grafts from the back, abdomen and thigh, applied to the palm and fingers and retained for periods extending from several months to 17 years are studied. After the second year, the transplants display virtually complete recovery of the sensation for pain, touch, pressure and temperature. The hair roots in the transplants have varying thickness and reveal changes in the structure of the connective-tissue and outer epithelial sheath (Figs. 1, 2). The sebaceous glands are enlarged. Isolated sebaceous glands are encountered which do not communicate with the hair roots. In the upper layers of the corium bundles of myelin nerve fibers are observed, giving off small groups of 2-4 fibers each, with slightly ascending direction relative to the hair roots (Fig. 3). The nerve fibers break down into branches which are furthermore ramified into smaller branches, forming palisade-like endings along the outer epethelial sheath of the hair root (Figs. 4-8). They number 15-25, being usually thin, with a discrete number of thickenings, and resemble the normal fibers running along the hair roots of the donor site (Figs. 9, 10). No capsulated receptors, characteristic of the surrounding skin, are noted in the transplants. Hence, it is assumed that most likely, the endings of the regenerated nerve fibers along the hair roots, although uncapsulated and with identical structure, provide for perceiving the types of sensation, inherent of the hairy and glabrous human skin.
对7个局部皮瓣以及取自背部、腹部和大腿的6个游离皮肤移植片应用于手掌和手指，并保留数月至17年的不同区域进行了研究。第二年之后，移植片对疼痛、触觉、压力和温度的感觉几乎完全恢复。移植片中的发根粗细各异，结缔组织和外上皮鞘的结构也有变化（图1、2）。皮脂腺增大。可发现孤立的皮脂腺，它们与发根不相连。在真皮上层观察到有髓神经纤维束，每束发出2 - 4根小纤维束，相对于发根略有上升方向（图3）。神经纤维分支，进一步分支成更小的分支，沿发根的外上皮鞘形成栅栏状末梢（图4 - 8）。它们有15 - 25根，通常很细，有离散的增厚部分，类似于供区沿发根走行的正常纤维（图9、10）。在移植片中未发现周围皮肤特有的被囊感受器。因此，可以推测，沿着发根的再生神经纤维末梢，尽管没有被囊且结构相同，但很可能提供了对人类有毛和无毛皮肤固有的感觉类型的感知。
