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药物性再生障碍性贫血合并产气荚膜梭菌败血症

[Clostridium perfringens septicemia in drug-induced aplasia].

作者信息

Chèze S, Levaltier X, Reman O, Vergnaud M, Boutard P, Troussard X, Leporrier M

机构信息

Service d'hématologie clinique, CHU, Caen, France.

出版信息

Rev Med Interne. 1994;15(9):597-600. doi: 10.1016/s0248-8663(05)82506-8.

Abstract

Septicemia due to Clostridium perfringens during the course of acute leukemia is rare and often lethal particularly in childhood. Antibiotherapy is necessary but polymorphonuclear activity recovery is helpful. This can be done through transfusion or administration of colony stimulating factors. Here is a new case of such a septicemia in a 12 year-old female treated for acute lymphoblastic leukemia. Of particular interest is the favourable outcome despite a high risk situation.

摘要

急性白血病病程中由产气荚膜梭菌引起的败血症很罕见,且往往致命,尤其是在儿童期。抗生素治疗是必要的,但多形核细胞活性的恢复会有所帮助。这可以通过输血或给予集落刺激因子来实现。本文介绍了一名12岁急性淋巴细胞白血病女童发生这种败血症的新病例。特别值得关注的是,尽管处于高风险状态,但预后良好。

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