Shiah C J, Tsai D M, Liao S T, Siauw C P, Lee L S
Department of Internal Medicine, Taipei Municipal Jen-Ai Hospital, Taiwan, ROC.
Am J Kidney Dis. 1994 Dec;24(6):932-5. doi: 10.1016/s0272-6386(12)81064-x.
We report an adult case of asymptomatic Bartter's syndrome with the first presentation of hypokalemic paralysis triggered by gentamicin injection. Marked hypokalemia and hypomagnesemia associated with excessive kaliuresis and magnesiuria were found. Plasma renin activity and aldosterone concentration were high, but blood pressure was normal. Renal biopsy revealed hypercellularity of the renin-producing cell of the juxtaglomerular apparatus. Muscular paralysis subsided after potassium chloride supplementation. Hypokalemia was corrected with potassium and magnesium supplements and the use of diclofenac. To the best of our knowledge, there have been no reports of muscular paralysis associated with gentamicin in Bartter's syndrome.
我们报告一例成人无症状巴特综合征病例，首次表现为庆大霉素注射引发的低钾性麻痹。发现存在明显低钾血症和低镁血症，伴有尿钾和尿镁过多。血浆肾素活性和醛固酮浓度升高，但血压正常。肾活检显示球旁器产肾素细胞增生。补充氯化钾后肌肉麻痹消退。通过补充钾和镁以及使用双氯芬酸纠正了低钾血症。据我们所知，尚无关于巴特综合征中庆大霉素相关肌肉麻痹的报道。
