长期血浆置换。适应证、疗效及副作用分析。
Long-term plasma exchange. Analysis of indications, outcome and side effects.
作者信息
Karmochkine M, Bussel A, Léon A, Jarrousse B, Baudelot J, Guillevin L
机构信息
Service de Médecine Interne, Hôpital Avicenne, Bobigny.
出版信息
Ann Med Interne (Paris). 1994;145(5):373-5.
In order to determine the characteristics and the course of diseases treated with long-term plasmapheresis (e.g., more than 25 plasma exchanges), we retrospectively studied 850 patients who underwent plasmapheresis. Long-term plasma exchange was prescribed to 38 patients who failed to respond to conventional therapy; cryoglobulinemias, peripheral neuropathies and monoclonal gammopathies were their most frequent underlying diseases. Improvement was noted in 65.8% cases. Only minor side effects were observed and the risk/benefit ratio for such therapy was excellent.
为了确定接受长期血浆置换术（例如，超过25次血浆置换）治疗的疾病的特征和病程，我们回顾性研究了850例接受血浆置换术的患者。38例对传统治疗无反应的患者接受了长期血浆置换；冷球蛋白血症、周围神经病变和单克隆丙种球蛋白病是他们最常见的基础疾病。65.8%的病例有改善。仅观察到轻微的副作用，这种治疗的风险/效益比极佳。
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