Staessen J A, Fagard R, Amery A
Department of Molecular and Cardiovascular Research, University of Leuven, Belgium.
Am J Hypertens. 1994 Aug;7(8):685-94. doi: 10.1093/ajh/7.8.685.
This study investigated which life style factors were correlated with the level and the variability of systolic (SBP) and diastolic (DBP) pressure in a random population sample. Ten blood pressure readings were obtained at home in 405 men and 379 women (20 to 84 years). Each person's average pressure level was computed together with the standard deviation as index of variability. Sodium, potassium, and alcohol intake, smoking habits, social class, psychoemotional stress, and the calories spent at work and in sports were assessed from a questionnaire and from determinations on serum and on a 24-h urine sample. A P10 to P90 (10th and 90th percentile) increase of alcohol intake, as reflected by serum gamma-glutamyltransferase, was associated with a 3.2 +/- 0.9 mm Hg higher DBP in men and with a 3.1 +/- 1.6 mm Hg higher SBP and a 1.5 +/- 0.8 mm Hg higher DBP in women. A P10 to P90 increase in the calories spent in sports was accompanied by a decrease in pressure, averaging 1.5 +/- 0.8 mm Hg for DBP in men and 2.4 +/- 1.2 mm Hg and 1.8 +/- 0.8 mm Hg for SBP and DBP in women. A 2.2 +/- 0.7 mm Hg higher DBP was observed in women living in a working class area. After adjustment for age, the variability of DBP was inversely correlated with self-rated physical activity in men, whereas women living in a working class area showed a decreased SBP variability. In conclusion, in an affluent Western population, alcohol intake, participation in sports, and living in a working class area were identified as the life style factors of importance for the blood pressure level. By contrast, blood pressure variability, as measured in the present study, was only to a minor extent influenced by life style.
本研究调查了在一个随机人群样本中,哪些生活方式因素与收缩压(SBP)和舒张压(DBP)的水平及变异性相关。对405名男性和379名女性(年龄在20至84岁之间)进行了10次家庭血压测量。计算了每个人的平均血压水平,并将标准差作为变异性指标。通过问卷调查以及血清和24小时尿液样本检测,评估了钠、钾和酒精摄入量、吸烟习惯、社会阶层、心理情绪压力以及工作和运动消耗的卡路里。血清γ-谷氨酰转移酶反映的酒精摄入量从第10百分位数(P10)增加到第90百分位数(P90),男性的舒张压升高3.2±0.9 mmHg,女性的收缩压升高3.1±1.6 mmHg,舒张压升高1.5±0.8 mmHg。运动消耗的卡路里从P10增加到P90,血压随之降低,男性舒张压平均降低1.5±0.8 mmHg,女性收缩压和舒张压分别平均降低2.4±1.2 mmHg和1.8±0.8 mmHg。生活在工人阶级社区的女性舒张压高2.2±0.7 mmHg。在调整年龄后,男性舒张压的变异性与自我评估的身体活动呈负相关,而生活在工人阶级社区的女性收缩压变异性降低。总之,在富裕的西方人群中,酒精摄入量、参与运动以及生活在工人阶级社区被确定为对血压水平重要的生活方式因素。相比之下,本研究中测量的血压变异性仅在较小程度上受生活方式影响。