McGuire P K, Jones P, Harvey I, Bebbington P, Toone B, Lewis S, Murray R M
Department of Psychological Medicine and Genetics, Institute of Psychiatry and King's College Hospital, London, UK.
Schizophr Res. 1994 Sep;13(2):161-7. doi: 10.1016/0920-9964(94)90097-3.
The Present State Examination was used to assess the psychopathology of 23 psychotic patients who were cannabis positive on urinary screening, and 46 matched drug-free controls. Cases and controls were indistinguishable in terms of psychopathology, DSMIII diagnoses, onset of recent illness, the proportion of first admissions, ethnicity, and socio-economic class, differing only in their histories of substance use. These data suggest that psychosis which develops or recurs in the context of cannabis use does not have a characteristic psychopathology or mode of onset, and is not restricted to a particular ethnic or socio-demographic group. There is thus little evidence to support the validity of 'cannabis psychosis' as a diagnostic entity.
采用现状检查法评估了23名尿液筛查大麻呈阳性的精神病患者以及46名匹配的无毒品对照者的精神病理学状况。病例组和对照组在精神病理学、《精神疾病诊断与统计手册》第三版（DSMIII）诊断、近期疾病发作、首次入院比例、种族和社会经济阶层方面并无差异，仅在物质使用史方面有所不同。这些数据表明，在使用大麻的背景下发展或复发的精神病没有特征性的精神病理学或发病模式，也不限于特定的种族或社会人口群体。因此，几乎没有证据支持“大麻精神病”作为一个诊断实体的有效性。
