Sáez-Llorens X, Velarde J, Cantón C
Department of Infectious Diseases, Hospital del Niño, Panama City, Panama.
Clin Infect Dis. 1994 Aug;19(2):323-4. doi: 10.1093/clinids/19.2.323.
Two hundred forty-one children who had osteomyelitis during a 19-year period, 1974 through 1992, were identified by chart review. Acute osteomyelitis or chronic osteomyelitis was the diagnosis for 221 (92%) and 20 (8%) of the children, respectively. Bacteriologic etiology was documented in 137 (57%) of the cases. Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella species organisms, and Haemophilus influenzae type b were isolated from 97 (40%), 10 (4%), 8 (3%), and 7 (3%) of the children, respectively. S. aureus was the predominant microorganism in all age groups, whereas H. influenzae occurred only in children younger than 2 years of age. P. aeruginosa was recovered predominantly from children with a penetrating injury of the foot, while salmonella bone infections were diagnosed in patients with sickle cell disease. These data provide guidelines for the initial work-up for and management of osteomyelitis in children living in developing Latin American countries.
通过病历审查,确定了1974年至1992年这19年间患有骨髓炎的241名儿童。其中,分别有221名(92%)和20名(8%)儿童被诊断为急性骨髓炎或慢性骨髓炎。137例(57%)病例记录了细菌学病因。分别从97名(40%)、10名(4%)、8名(3%)和7名(3%)儿童中分离出金黄色葡萄球菌、铜绿假单胞菌、沙门氏菌属微生物和b型流感嗜血杆菌。金黄色葡萄球菌是所有年龄组中的主要微生物,而流感嗜血杆菌仅出现在2岁以下儿童中。铜绿假单胞菌主要从足部穿透伤儿童中分离得到,而沙门氏菌骨感染则在镰状细胞病患者中被诊断出来。这些数据为拉丁美洲发展中国家儿童骨髓炎的初始检查和管理提供了指导方针。