Goudard F, Paquet F, Durand J P, Milcent M C, Germain P, Pieri J
Laboratoire de Biochimie et de Radiobiochimie, GERMETRAD, Université de Nantes, France.
Biochem Mol Biol Int. 1994 Aug;33(5):841-51.
In the lobster, most of the radionuclides ingested with contaminated food are concentrated in the digestive gland. Americium-241 accumulation in the hepatopancreas of the lobster was studied during the digestive cycle. Fractionations of cytosols at different times after ingestion of radioactive preys were performed by gel permeation chromatography to determine the distribution of 241Am in the different macromolecular components. 241Am was associated with ferritin during the whole digestive cycle. This observation suggests a correlation between 241Am distribution pathways and iron metabolism. The distribution of 241Am present in the other cytosolic proteins followed two major steps of accumulation which may be correlated to the evolution of the two main cellular types playing an important role in the digestive cycle (B and R type cells).
在龙虾中，摄入受污染食物所摄取的大多数放射性核素都集中在消化腺中。在消化周期中研究了龙虾肝胰腺中镅 - 241的积累情况。通过凝胶渗透色谱法对摄入放射性猎物后不同时间的细胞溶质进行分级分离，以确定镅 - 241在不同大分子成分中的分布。在整个消化周期中，镅 - 241都与铁蛋白相关。这一观察结果表明镅 - 241的分布途径与铁代谢之间存在相关性。存在于其他细胞溶质蛋白中的镅 - 241的分布遵循两个主要的积累步骤，这可能与在消化周期中起重要作用的两种主要细胞类型（B型和R型细胞）的演变相关。
