Woodruff P W, Morton J, Russell G F
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, United Kingdom.
Int J Eat Disord. 1994 Sep;16(2):205-9. doi: 10.1002/1098-108x(199409)16:2<205::aid-eat2260160212>3.0.co;2-c.
A 19-year-old female patient with anorexia nervosa developed profound weight loss over 1 year associated with vegetarianism and excessive exercise. There was severe wasting and proximal muscle weakness in the legs and bilateral weakness of eye closure. A purpuric rash developed due to vitamin C deficiency. This case demonstrates a new neurological sign in anorexia nervosa indicating a weakness of the orbicularis oculi muscles as part of a more general myopathy. The myopathic and scorbutic features may have a common pathogenesis.
一名19岁神经性厌食症女性患者在1年多的时间里体重急剧下降,这与素食主义和过度运动有关。患者出现严重消瘦,腿部近端肌肉无力,双眼睑闭合无力。因维生素C缺乏出现了紫癜疹。该病例显示了神经性厌食症一种新的神经学体征,提示眼轮匝肌无力是更广泛肌病的一部分。肌病和坏血病特征可能有共同的发病机制。